Table 1.
Summary of IS modulation in ISCs and EBs on the responses of fly physiological, metabolic, and gene expression parameters.
| Parameters | Inhibition | Activation |
|---|---|---|
| Lifespan |
|
|
| Starvation resistance |
|
|
| Malnutrition resistance 1% sucrose |
|
|
| Malnutrition resistance 1% autolyzed yeast |
|
|
| Malnutrition resistance 0.5% S and 0.5% AY |
|
|
| Feeding, Fecundity |
|
|
| Body glucose, glycogen |
|
|
| dilp2, dilp5, tobi |
|
|
| dilp6 |
|
|
| akh |
|
|
| upd2, upd3, soc36 |
|
|
| spi |
|
|
| vn |
|
|