Figure 8.

(A) Levels of mRNA expression of Nf-kB and Nrf2 and (B) NF-κB-target genes (Tnfα, Il6 and Mcp1) in the in vitro differentiated adipocytes obtained from HMSC from non-obese (n = 6) and morbidly obese subjects (n = 6) incubated with 0, 25 and 50 μg/mL of oxLDL for 24h. ^a p < 0.05: significant differences with regard to 0 μg/mL oxLDL within non-obese subjects. ^b p < 0.05: significant differences with regard to 25 μg/mL oxLDL within non-obese subjects. ^c p < 0.05: significant differences with regard to 0 μg/mL oxLDL within morbidly obese subjects. ^d p < 0.05: significant differences with regard to 25 μg/mL oxLDL within morbidly obese subjects. * p < 0.05: significant differences for each dose between non-obese and morbidly obese subjects; (C) levels of mRNA expression of Nf-kB and Nrf2 in visceral mature adipocytes obtained from visceral adipose tissue of non-obese (n = 10) and morbidly obese subjects (n = 10). ¹ p < 0.05: significant differences with regard to non-obese subjects.