Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Diagram showing neuronal differentiation of NCSCs and PTXF mechanisms. The nuclear increase of NF-κB-c-REL directs differentiation into the glutamatergic neuronal fate. c-Rel inhibition by PTXF leads to a switch in the gene expression program from the neuronal fate, resulting in the cell fate shift, cell death or both. PTXF: pentoxifylline, NCSCs: neural crest-derived stem cells, NSCs: neural stem cells.
