Table 3.

Proteins that regulate potassium ion dynamics involved in carcinogenesis with potential modulators.

The Name of Proteins		Modulators
Voltage-gated potassium channel (VGKCs)		Astemizole
Calcium-activated potassium channel	BK channel (Maxi-K, slo1)	Charybdotoxin (blocker) [166]
	SK channels	Rottlerin (mallotoxin) (activator) [167]
	IK channel
Inwardly rectifying potassium channel	The renal outer medullary potassium channel (ROMK)	Nicorandil (could be used as adjuvant therapy to anticancer to prevent cardiotoxicity) [168,169]
	G protein-coupled inwardly rectifying potassium channels (GIRKs)
	ATP-sensitive potassium channel (KATP channel)
Tandem pore domain potassium channel		Fluoxetine [170,171,172]