Figure 4.

Functional enrichment analysis. A, Workflow for prediction of long noncoding RNA (lncRNA) function using the proposed network‐based guilt‐by‐association approach that incorporates known protein‐protein and gene regulatory interactions to derive a coexpressed interactome. Coexpressed communities were then identified and modules containing at least 1 lncRNA were subject to functional enrichment analysis. B, Two clusters were identified containing at least 1 lncRNA. For each cluster, representative Gene Ontology terms are listed in the tables and are grouped by a broad functional classification. Overall, the node size is proportional to degree of nodes and nodes are colored blue to red by log2 of degree. Nodes are labeled by the gene/lncRNA name if degree > 50