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. 2020 Apr 8;12(4):913. doi: 10.3390/cancers12040913

Figure 6.

Figure 6

The association of PGK1 expression with metastasis status and prognosis of patients with breast cancer. (A) The association of PGK1 expression with the metastasis status of breast cancer patients was determined by the analysis of GSE58812 and GSE102484 datasets. The probe of 200738_s_at was used to obtain gene expression values in each dataset. The bars represent the mean ± SD; Statistical significance was determined by a two-tailed Mann–Whitney test. (B) Elevated PGK1 expression levels in brain metastases compared with those in primary tumors was determined by the analysis of a GSE125989 dataset. The probe of 200738_s_at was used to obtain gene expression values in this dataset. The bars represent the mean ± SD; Statistical significance was determined by a Wilkoxon matched-pairs signed-rank test. (C) Kaplan–Meier survival curve showing poor overall survival (OS) in the PGK1-high population of patients with breast cancer. The survival analysis was performed using DRUGSURV.