Figure 6.

Identification of downstream adipocyte enhancer‐binding protein 1 (AEBP1) targets in endothelial cells. A, Venn diagram showing genes whose expression was downregulated by AEBP1 knockdown in human umbilical vein endothelial cells (HUVECs). B, Quantitative RT‐PCR validating the microarray results for the indicated genes. Expression levels are normalized to ACTB expression. Shown are means of 3 replications. C, Relative expression of the indicated genes in HUVECs ectopically expressing LacZ or the indicated AEBP1 variant. Expression levels are normalized to ACTB expression. Shown are means of 3 replications. Error bars depict SEMs. AQP, aquaporin; GJA4, gap junction protein, alpha‐4; POSTN, periostin; SELE, selectin E; SEMA3G, semaphorin 3G; siCtrl, control siRNA