Table 1.

Correlation of clinicopathologic features with tumor microRNA (miR)‐375 and thymidylate synthase (TYMS) mRNA levels in a cohort of colorectal cancer patients (n = 367)

	miR‐375			TYMS
	High	Low	P value	High	Low	P value
Gender
Female	91	84	.495	93	82	.27100
Male	93	99		91	101
Age (y)
<50	28	13	.005	24	17	.03500
50‐70	68	94		69	93
>70	88	76		91	73
Colon polyps present
Yes	32	31	.426	30	33	.08300
No	52	63		49	66
Unknown	100	89		105	84
Lymphatic invasion
Yes	68	67	.982	60	75	.24100
No	98	97		105	90
Unknown	18	19		19	18
Cancer status
With tumor	41	46	.534	36	51	.12400
Tumor‐free	116	105		114	107
Unknown	27	32		34	25
Preoperative pretreatment CEA level (ng/mL)
<5.9	85	79	.661	79	85	.01300
≥5.9	37	34		27	44
Unknown	62	70		78	54
Tumor stage
Stage I + II	105	92	.336	119	77	.00072
Stage III + IV	75	84		60	100
Unknown	4	7		5	6
Venous invasion
Yes	37	45	.508	36	46	.23600
No	120	116		119	117
Unknown	27	22		29	20

Bold indicates significant P values

Data were subjected to the chi‐Square test