Figure 3.

Antitumor activity of antifibroblast growth factor 19 (FGF19) Abs in hepatocellular carcinoma xenograft mouse models. A‐C, G1A8 inhibited tumor growth in a cell line‐derived xenograft model established using luciferized Hep3B‐Luc23 cells in NOD SCID mice (n = 6/group). D, E, G1A8 inhibited tumor growth in a xenograft model established using WT Hep3B cells in NSG mice. Tumor volumes and survival curves are shown. Time points for Ab treatment are marked by arrows. Control (Ctrl.) IgG, rituximab