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. 2020 Apr 3;12(4):868. doi: 10.3390/cancers12040868

Figure 1.

Figure 1

High TIE2 expression in the primary tumor is associated with an increased time to the detection of metastases in breast cancer patients. Analysis of metastasis-free survival using the PROGgene database. The median TIE2 mRNA level in the primary tumor was taken as a bifurcation point. Results are presented as (A) Kaplan–Meier plots for the Sotiriou (GSE2990) and Loi datasets (GSE6532), or as (B) a forest plot, indicating the overall hazard ratio (HR) for metastasis-occurrence and 95% confidence interval (CI). Survival analysis was performed using a log-rank test, ‡ p < 0.078, and * p < 0.05.