Figure 4.

Effects of localized RT, Vinorelbine, and RT/Vinorelbine on the DNA repair pathway, receptor tyrosine kinases (RTKs), and its downstream targets in the HCC19-0913 model. Mice were subcutaneously implanted with HCC19-0913 tumors on both flanks and were irradiated with 8 Gy on the right flank, in the presence or absence of 3 mg/kg Vinorelbine. Tumor tissues were collected on day 2 post-RT, and lysates were subjected to Western blot and quantification analyses, as described in Appendix A. The intensity ratio of each band is expressed as the fold change relative to control. Representative blots are shown.