Table 3.

Summary of the biomarkers of thyroid irAE identified in the study

Factors significantly increased 4 wk after initial ICI treatment in thyroid irAE

Tg, TgAb, TPOAb

Factors significantly higher at baseline in thyroid irAE

IL‐1β, IL‐2, GM‐CSF

Factors significantly decreased 4 wk after initial ICI treatment in thyroid irAE

IL‐8, G‐CSF, MCP‐1

Abbreviations: G‐CSF, granulocyte colony‐stimulating factor; GM‐CSF, granulocyte–macrophage colony‐stimulating factor; MCP‐1, monocyte chemoattractant protein; Tg, thyroglobulin; TgAb, anti‐thyroglobulin autoantibody; TPOAb, anti‐TPO autoantibody.