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Anticancer effects of (A) L‐OHP and (B) curcumin on each HCT116 cell line in vitro. The IC50 values of L‐OHP and curcumin on each HCT116 cell line (KRASw/TP53w, KRASm/TP53w and KRASm/TP53‐) at 72 hours post−treatment. Data represent means ± SD (n = 3). *P < 0.01, as compared to KRASw/TP53w HCT116; #P < 0.01, as compared to KRASm/TP53w HCT116; **P < 0.01, as compared to KRASw/TP53w HCT116 and KRAS m/TP53w HCT116
