Figure 1.

(-)-Epigallocatechin-3-gallate (EGCG) promotion of bone fracture healing in rats. The images of X-ray and micro-computed tomography (μ-CT). (A) The X-ray radiographic analysis showed a clear fracture gap at weeks 0, 2, and 4 in the control group, and this fracture was gradually blurred at weeks 2 and 4 in the EGCG treated group. Arrows indicate the fracture site. (B) The results of μ-CT analysis also showed a gradual union of fracture gap at the end of weeks 2 and 4 after treatment. Compared to the control group, the fracture was united at the end of week 4 after the EGCG treatment, suggesting that fracture healing process was accelerated by EGCG.