Table 2.
Molecular Tools for Selecting Patients in Precision Medicine-Based Basket Trials | |
---|---|
Clinical Trial | Molecular Tools |
Bisgrove [75] | Immunohistochemistry, Fluorescence in situ hybridization microarray |
IMPACT [76] | PCR-based genomics and NGS |
SHIVA [64] | Targeted NGS-based |
MOSCATO [39] | Targeted NGS-based, RNA Seq |
MyPathway [77] | Genomic testing |
Profiler [78] | Targeted NGS-based |
I-PREDICT [79] | Targeted NGS-based, ctDNA |
WINTHER [80] | Targeted NGS-based, Transcriptomic |