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. 2020 Apr 20;9(4):1020. doi: 10.3390/cells9041020

Figure 1.

Figure 1

LncRNA MALAT1 is over-expressed in liver cancer tissues and cell lines. (A) Differential MALAT1 expression in HCC (n = 35, median 3.352) followed by liver cell dysplasia (n = 17, median 3.32), cirrhosis (n = 13, median 2.21) and normal liver (n = 10, median 1.456) from analyses of the Oncomine Wurmbach liver dataset. 0 = Normal; 1 = cirrhosis; 2 = hepatocellular carcinoma; 3 = liver cell dysplasia. (B) Graphical representation of relative MALAT1 mRNA expression levels in normal liver cell line THLE-2, HCC Huh7, Mahlavu, SK-Hep1 and HepG2 human hepatoblastoma cell lines. U6 served as internal control. (C) Comparative analyses in paired clinical HCC and non-tumor liver samples using quantitative PCR method. * p < 0.05, ** p < 0.01; T, tumor; NT, non-tumor.