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. 2020 Apr 18;9(4):1007. doi: 10.3390/cells9041007

Figure 5.

Figure 5

Reinnervation does not originate from lacerated tibial and peroneal nerves but is resulted from sprouting from the axons innervating neighboring areas. (A,B) Box plots and paired individual values of normalized paw lifting latencies, measured using calibrated pinprick (A) and mechanical threshold, measured using VF (B) before SNI surgery (baseline); three and 40 days after the first SNI and three days after repeated SNI. Note no values for the mechanical threshold 3 days after SNI (B) as all animals did not respond to the cut off value of the VF. Note no significant difference between the values of the mechanical threshold and paw lifting duration measured 40 days after SNI and three days after the second SNI. The baseline value represents the mean values of three tests performed at three consecutive days before SNI or sham surgery. All of the values were normalized to the baseline value. ** p < 0.01; * p < 0.05; ns—not significant, RM one-way ANOVA. Box plots presented in the figures depict mean; 25th; 75th percentile and SD.