Table 3.
Studies of plant extracts for the biosynthesis of anticancer AgNPs (brain, cervical and colon cancers cell lines).
| Cancer | Plant | Part Used | NP Size/NP Shape | Incubation Time | Cell Line | IC50 | Ref. |
|---|---|---|---|---|---|---|---|
| Brain Cancer | Butea monosperma | Leaf | 20–80 nm/spherical | 2 h | HNGC2 | Dose dependent | [101] |
| Cervical Cancer | Azadirachta indica | Leaf | 2–18 nm/triangular, hexagonal | - | Siha | ≤4.25 μg/mL | [106] |
| Acorous calamus | Rhizome | 31.86 nm/spherical | 20 h | HeLa | Dose dependent | [107] | |
| Azadirachta indica | Leaf | <40 nm/spherical | 6 h | Dose dependent | [95] | ||
| Calotropis gigantea | Latex | 5–30 nm/spherical | 24 h | Dose dependent | [108] | ||
| Cymodocea serrulata | Whole | 17–29 nm/spherical | 2 h | 107.7 (GI50) | [109] | ||
| Heliotropium indicum | Leaf | 80–120 nm/spherical | 2 h | 20 μg/mL | [110] | ||
| Melia azedarach | Leaf | 78 nm/cubical, spherical | 10 min | 300 μg/mL (LD50) | [23] | ||
| Moringa olifera | Stem bark | 38–40 nm/spherical, pentagonal | 24 h | Dose dependent | [25] | ||
| Podophyllum hexandrum | Leaf | 14 nm/spherical | 30–150 min | 20 μg/mL | [111] | ||
| Sargassum vulgare (algae) | Whole | 10 nm/spherical | 3 h | Dose dependent | [112] | ||
| Syzygium cumini | Flower | <40 nm/spherical | 6 h | Dose dependent | [95] | ||
| Colon Cancer | Plumeria alba | Flower | 36.19 nm/spherical | 30 min | COLO 205 | 5.5 μg/mL | [113] |
| Rosa indica | Petal | 23.52–60.83 nm/spherical | 1 h | HCT 15 | 30 μg/mL | [114] | |
| Vitex nigundo | Leaf | 22 nm/spherical | 4 h | 20 μg/mL | [115] | ||
| Citrullus colocynthis | Leaf | 13.37 nm/spherical | 24 h | HCT-116 | >30 μg/mL | [103] | |
| Roots | 7.39 nm/spherical | 24 h | >30 μg/mL | ||||
| Seeds | 16.57 nm/Spherical | 24 h | >30 μg/mL | ||||
| Fruit | 19.26 nm/spherical | 24 h | 21.2 μg/mL | ||||
| Commelina nudiflora L. | Whole | 24–80 nm/spherical, triangular | 24 h | 100 μg/mL | [61] | ||
| Gymnema sylvestre | Leaf | -/spherical | 24 h | HT29 | 85 μg/mL | [116] | |
| Ulva lactuca (algae) | Whole | 56 nm/spherical | 10 min | 49 μg/mL | [105] |
NP—nanoparticle.