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. 2020 Mar 26;9(4):806. doi: 10.3390/cells9040806

Figure 4.

Figure 4

Downregulation of GAL1 affected cancerous behavior in the BFTC-909 and T24 cells and effects of different concentrations of GAL1 recombinant protein (0–3 μg/mL) on the J82 cells. GAL1 knockdown cells produced using lentiviruses exhibited a reduction in migration and invasiveness in the BFTC-909 (A) and T24 cells (B). (C) Viability of the J82 cells at different concentrations of GAL1 recombinant protein (0–3 μg/mL) after incubation for 24 h. (D) After 24 h of treatment with GAL1 recombinant protein (1–2 μg/mL), the percentages of migration of and invasion by the J82 cells significantly increased compared with the controls (Mock: cells treated with vehicle DMSO). Scale bar = 20 μm. * p < 0.05, # p < 0.001.