Table 2.
Univariate logistic regression analysis of the predictive value of the selected gene signature in preoperative chemoradiotherapy (PCRT) responders (p < 0.05).
| Variable 1 | N 2 | Coef 3 | SE 4 (Coef) | Z-Score | p-Value |
|---|---|---|---|---|---|
| Candidate genes | |||||
| FGFR3_GNA11_H3F3A_IL12A_IL1R1_IL2RB_NKD1_SGK2_SPRY2 (low vs. high) | 60 | 3.204371 | 0.693663 | 4.619491 | 3.85 × 10−6 |
| Clinicopathological features | |||||
| GENDER (Male vs. Female) | 60 | 1.170379 | 0.549265 | 2.130811 | 3.31 × 10−2 |
| GRADED_DESCRIPTION (Moderate vs. Well) | 59 | −0.787079 | 0.783116 | −1.00506 | 3.15 × 10−1 |
| CLIN_T_TNM (T2 vs. T3-T4) | 60 | −1.386294 | 1.185853 | −1.16903 | 2.42 × 10−1 |
| CLIN_N_TNM (N0-N1 vs. N2) | 60 | −0.633724 | 0.528492 | −1.19912 | 2.30 × 10−1 |
| CLIN_M_TNM (M0 vs. M1) | 60 | 16.8437 | 1696.73436 | 0.009927 | 9.92 × 10−1 |
| PATH_T_TNM (Tis-T0-T1-T2 vs. T3) | 60 | −2.233592 | 0.605857 | −3.68666 | 2.27 × 10−4 |
| PATH_N_TNM (N0-N1 vs. N2) | 56 | −0.04879 | 0.956183 | −0.05103 | 9.59 × 10−1 |
| PATH_M_TNM (M0 vs. M1) | 60 | −15.39617 | 1455.39756 | −0.01058 | 9.92 × 10−1 |
1 Abbreviations: CLIN, clinical; PATH, pathological; T, tumor; N, node; M, metastasis. 2 N, number of samples. 3 Coef, coefficient. 4 SE, standard error.