Table A1.
Top 90 genes differentially expressed between ALI-Yes and ALI-No identified by Limma topTable function.
| Gene SYMBOL | Fold 1 (Yes/No) | Probability 2 | Gene Symbol | Fold (Yes/No) | Probability | Gene Symbol | Fold (Yes/No) | Probability |
|---|---|---|---|---|---|---|---|---|
| LDHD | 0.351 | 65.7 | MMP3 | 1.346 | 19.0 | GRHL3 | 0.481 | 11.9 |
| SORCS2 | 2.233 | 62.9 | TRIM56 | 1.241 | 19.0 | LRRC73 | 1.438 | 11.8 |
| NELL2 | 0.390 | 60.7 | AAMDC | 1.420 | 18.9 | FBXO2 | 1.878 | 11.7 |
| ACSF2 | 1.778 | 52.5 | TMPRSS7 | 2.135 | 18.9 | CYB561A3 | 1.388 | 11.2 |
| MMP1 | 1.457 | 45.7 | ITGA3 | 1.701 | 18.6 | ITGA2 | 1.221 | 11.1 |
| SERPINE1 | 2.103 | 45.6 | TNK1 | 1.717 | 18.2 | IQCE | 1.415 | 11.1 |
| DDR1 | 1.569 | 45.4 | CHST3 | 1.232 | 17.8 | ZNF114 | 1.927 | 11.0 |
| CHST15 | 1.304 | 44.3 | MCOLN3 | 2.266 | 17.0 | PRODH | 0.414 | 11.0 |
| GRINA | 1.257 | 38.5 | HECTD1 | 0.877 | 16.5 | ME1 | 0.758 | 10.8 |
| CCDC30 | 1.313 | 38.3 | PTGER1 | 0.680 | 15.8 | NBPF3 | 1.539 | 10.8 |
| ZNF704 | 2.084 | 33.4 | PPP2R2B | 2.034 | 15.6 | ASB4 | 0.806 | 10.6 |
| RNF5P1 | 1.425 | 33.3 | GPR107 | 1.662 | 15.5 | LYRM1 | 0.910 | 10.6 |
| APCDD1L | 2.075 | 32.3 | SLC16A9 | 0.595 | 15.4 | CYP4F22 | 0.276 | 10.6 |
| CYP24A1 | 1.540 | 31.3 | MCRIP1 | 1.522 | 15.1 | XYLT2 | 1.176 | 10.4 |
| REPS2 | 1.951 | 29.1 | DLL1 | 1.428 | 14.8 | KLC4 | 1.482 | 10.2 |
| CAMK2N1 | 1.613 | 27.1 | CDCA7L | 1.440 | 14.8 | CGB5 | 2.487 | 10.2 |
| TINAGL1 | 1.751 | 27.1 | FOXC2 | 1.850 | 14.6 | EVA1A | 1.926 | 10.1 |
| KLK14 | 0.269 | 26.1 | RTN4RL2 | 1.204 | 14.4 | MDFIC | 0.780 | 10.0 |
| TGFBI | 1.192 | 23.2 | SPECC1 | 1.479 | 14.0 | PRKCH | 0.813 | 9.9 |
| NOS3 | 0.606 | 21.3 | NCS1 | 1.581 | 13.6 | SLC2A6 | 1.359 | 9.8 |
| ZDHHC21 | 0.625 | 21.1 | CCM2 | 1.197 | 13.5 | EFHB | 0.487 | 9.8 |
| FSTL3 | 1.753 | 20.8 | UPK1A | 0.349 | 13.3 | EPHB2 | 2.235 | 9.8 |
| AUH | 1.562 | 20.7 | GLB1 | 1.318 | 13.1 | FREM1 | 0.681 | 9.6 |
| ITGB4 | 1.320 | 20.3 | SYK | 0.633 | 13.0 | MFSD6 | 0.789 | 9.5 |
| C4orf26 | 2.344 | 20.2 | GLTP | 0.795 | 12.8 | GUCA2B | 0.728 | 9.5 |
| GPAT3 | 0.680 | 20.1 | COL4A6 | 1.842 | 12.7 | ZBTB18 | 0.889 | 9.4 |
| RRAS | 1.308 | 19.6 | BMP8B | 1.412 | 12.5 | NELFB | 1.364 | 9.2 |
| GPRC5D | 0.672 | 19.4 | PDPN | 1.585 | 12.5 | LYN | 1.207 | 9.1 |
| SEMA3G | 0.731 | 19.3 | HPSE | 0.636 | 12.1 | ABHD12 | 0.812 | 9.0 |
| PRRC2A | 1.329 | 19.2 | SLC43A2 | 1.763 | 12.0 | TMEM63C | 0.565 | 8.9 |
1 Transformed from log2-fold-change (LogFC) 2 Calculated from B statistic ((EXP(B)/(1 + EXP(B))) ∗ 100).