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. 2020 Mar 31;12(4):848. doi: 10.3390/cancers12040848

Figure 1.

Figure 1

Genomic alterations across breast cancers. (A) Frequency of genomic alteration (mutation and copy number variation) in the 147 breast cancer driver genes across the TCGA pancancer breast cancer dataset (n = 1033); and stratified by oestrogen receptor (ER) status (in magnified plot): ER positive, n = 795; ER negative, n = 238. Top ten most frequently mutated genes in (B) Invasive Carcinoma-No Special Type (IC-NST) [15]; (C) Invasive Lobular Carcinoma (ILC) [15]; and, (D) Metaplastic breast cancer [36,37,38].