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. 2020 Apr 19;12(4):1005. doi: 10.3390/cancers12041005

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparison between CTC levels as detected by the metabolic-based assay (MBA) and CellSearch (CS) and imaging. This plot shows the CTC count for individual patients at baseline (T0) and follow-up (T1), compared with their response at the first follow-up imaging. (CR/PR/SD = Complete Response/Partial Response/Stable Disease; PD = Progressive Disease. Statistical significance was calculated by Mann-Whitney test (*** p = 0.0001, * p = 0.027, ns = not significant (CS-CTCs: p = 0.05; MBA-CTCs: p = 0.07).