Table 3.
Concordance of CTC status between the metabolism-based assay (MBA) and CellSearch (CS) method at baseline (T0) and follow-up (T1), using respective cut-offs.
| Left Panel | Right Panel | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Time-Point | Cell Population | Cut-Off | CS | Tot | Time-Point | Cell Population | Cut-Off | CS | Tot | ||
| <5 | ≥5 | <5 | ≥5 | ||||||||
| T0 a | T0 c | ||||||||||
| MBA | <6 | 10 | 3 | 13 | MBA-E+ | <6 | 12 | 4 | 16 | ||
| ≥6 | 4 | 5 | 9 | ≥6 | 2 | 4 | 6 | ||||
| Tot | 14 | 8 | 22 | Tot | 14 | 8 | 22 | ||||
| T1 b | T1 d | ||||||||||
| MBA | <6 | 11 | 3 | 14 | MBA-E+ | <6 | 14 | 3 | 17 | ||
| ≥6 | 5 | 2 | 7 | ≥6 | 2 | 2 | 4 | ||||
| Tot | 16 | 5 | 21 | Tot | 16 | 5 | 21 | ||||
a Kappa = 0.330 (fair agreement); SE of kappa = 0.205; 95% CI from −0.071 to 0.732; Number of observed agreements: 15 (68.2% of the observations); b Kappa = 0.077 (poor agreement); SE of kappa = 0.218; 95% CI from −0.351 to 0.504; Number of observed agreements: 13 (61.9% of the observations); c Kappa = 0.377 (fair agreement); SE of kappa = 0.205; 95% CI from −0.025 to 0.780; Number of observed agreements: 16 (72.7% of the observations); d Kappa = 0.295 (fair agreement); SE of kappa = 0.243; 95% CI from −0.180 to 0.771; Number of observed agreements: 16 (76.2% of the observations).