Table 4.
PFS and OS by CTC count for metabolism-based assay (MBA) and CellSearch (CS) method at baseline (T0) and follow-up (T1), using respective cut-offs.
| Group | MBA-CTC < 6 | MBA-CTC ≥ 6 | p-Value | CS-CTC < 5 | CS-CTC ≥ 5 | p-Value |
|---|---|---|---|---|---|---|
| T0 | ||||||
| N (%) | 17 (63) | 10 (37) | 14 (63.6) | 8 (36.4) | ||
| Median PFS (days) | 306 | 123 | <0.0001 | 262 | 131 | 0.0146 |
| Median OS (days) | >600 | 243 | 0.0003 | >600 | 227 | 0.01 |
| T1 | ||||||
| N (%) | 18 (69.2) | 8 (30.8) | 17 (77.3) | 5 (22.7) | ||
| Median PFS (days) | 266 | 139 | 0.0086 | 260 | 119 | 0.0152 |
| Median OS (days) | >600 | 209 | 0.0301 | >600 | 191 | 0.0636 |