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PFS and OS according to the combined application of the metabolism-based assay (MBA) and CellSearch (CS).
| Group | 1-Double < Cut-Off | 2-Double ≥ Cut-Off | 3-CS Only ≥ Cut-Off | 4-MBA Only ≥ Cut-Off |
|---|---|---|---|---|
| T0 | ||||
| N (%) | 10 (45.5) | 5 (22.7) | 3 (13.6) | 4 (18.2) |
| Median PFS (days) | 323.5 | 112 | 146 | 149.5 |
| Median OS (days) | > 600 | 184 | 234 | 248 |
| T1 | ||||
| N (%) | 11 (52.4) | 2 (9.5) | 3 (14.3) | 5 (23.8) |
| Median PFS (days) | 264 | 35.5 | 127 | 140 |
| Median OS (days) | >600 | 113.5 | 278 | 234 |
