Table 6.
PFS and OS by the CTC status before and after therapy for the metabolism-based assay (MBA) and the CellSearch (CS).
| Group | 1-CTC < Cut-Off at All Time Points | 2-CTC ≥ Cut-Off at All Time Points | 3-CTC < Cut-Off at T0 + CTC ≥ Cut-Off at T1 | 4-CTC ≥ Cut-Off at T0 And CTC < Cut-Off at T1 |
|---|---|---|---|---|
| MBA | ||||
| N (%) | 12 (52.2) | 2 (8.7) | 3 (13.0) | 6 (26.1) |
| Median PFS (days) | 351 | 35.5 | 146 | 129 |
| Median OS (days) | >600 | 113.5 | >600 | 283 |
| CS | ||||
| N (%) | 8 (47.1) | 3 (17.6) | 2 (11.8) | 4 (23.5) |
| Median PFS (days) | 262 | 43 | 243.5 | 144 |
| Median OS (days) | >600 | 184 | 469.5 | 227 |