Figure 5.

Validation of image registration and hybrid E/M score evaluation. (a) Registration errors (nm) on pairs of VIM and pan-CK virtual slides. E/M scores computed on lung (b), and urothelial (c) carcinoma samples at 10× (dots) and 5× (overlapping squares) magnification levels related to the registration error. Dots are not visible in cases of perfect match between the two scores. (d) Negative correlation between E-cad score and E/M score in urothelial carcinomas (Pearson r = −0.90, n = 16).