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. 2020 Apr 10;12(4):939. doi: 10.3390/cancers12040939

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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MRI-based staging of the M5-T1 MM model. M5-T1 tumor (T, and yellow arrows) was present as omental cakes and nodules attached to the stomach (STO) and spleen (S) on both coronal (A) and axial images (B). M5-T1 tumor was also characterized by the presence of metastatic tumor development into the liver parenchyma (L) and along the portal vein. Note the changes in volume and white pulp vs. red pulp signal intensity of the spleen in the tumor-bearing rat in comparison to normal rat spleen.