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Analysis of G protein dependency. (a) PTX-mediated inhibition of FPR1-mediated changes in cAMP generation. (a) Maximum FPR1-mediated inhibition of forskolin-induced cAMP formation was completely prevented in cells pretreated for 16 h with 100 ng/mL PTX. (b) Effect of 1 µM FR preincubation for 1 h on IP-1 production induced by the phospholipase C activator m-3M3FBS. Data points represent the mean ± SEM.
