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Most frequent non-driver gene mutations. (A) For the whole patient cohort (n = 68), and for each neoplasia separately, (B) polycythemia vera (PV) (n = 16), (C) secondary myelofibrosis (SMF) (n = 11), (D) primary myelofibrosis (PMF) (n = 16), and (E) essential thrombocythemia (ET) (n = 25). DTA genes (DNMT3A, TET2, ASXL1) were the most frequently mutated in both the whole cohort and individual neoplasias. Hatched bars represent the sum of mutations in the DTA genes.
