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. 2020 Mar 25;10(4):497. doi: 10.3390/biom10040497

Table 2.

Diagnostic accuracy of CSF ubiquitin in the distinction between neurodegenerative dementias.

AUC Cut-off (ng/mL) Sens (%) Spec (%)
Prion Disease vs. Controls 0.949 ± 0.020 > 51.1 88.1 96.4
AD vs. Controls 0.925 ± 0.032 > 42.5 86.8 88.5
Prion Disease vs. AD 0.848 ± 0.035 > 68.3 77.4 89.5
Prion Disease vs. FTD 0.948 ± 0.020 > 54.6 85.7 96.7
AD vs. FTD 0.880 ± 0.044 > 45.7 86.8 80