Table 3.
Association between patient characteristics and local infectious complication.
| No infectious complicationn=255 (%) | Infectious complicationn=41 (%) | UnadjustedOR (95% CI) | P value | |
|---|---|---|---|---|
| Age, mean SD | 72.9 (14) | 71.2 (14.5) | 0.99 (0.97–1.02) | 0.48 |
| Male gender | 122 (47.8) | 22 (53.7) | 1.26 (0.65–2.45) | 0.49 |
| Relevant comorbiditya | ||||
| – Diabetes | 49 (19.2) | 9 (22) | 1.18 (0.53–2.64) | 0.68 |
| – COPD | 23 (9) | 7 (17.1) | 2.08 (0.83–5.21) | 0.12 |
| – Immunodeficiencyb | 2 (0.8) | 0 | NA | 1 |
| Previous cholecystectomy, n (%) | 67 (26.3) | 8 (19.5) | 0.68 (0.30–1.55) | 0.36 |
| Tokyo severity score | 0.75 | |||
| – Grade I | 57 (22.4) | 10 (24.4) | reference | |
| – Grade II | 177 (69.4) | 29 (70.2) | 0.93 (0.43–2.03) | |
| – Grade III | 21 (8.2) | 2 (4.9) | 0.54 (0.11–2.69) | |
| Timing ERCP after admission, median in days (IQR) | 2 (1–3) | 2 (1–3) | 0.98 (0.83–1.15) | 0.79 |
| Papillotomy | 236 (92.5) | 38 (92.7) | 1.02 (0.29–3.61) | 0.98 |
| Stent used to retrieve adequate drainage | 41 (16.1) | 7 (17.1) | 1.08 (0.45–2.59) | 0.87 |
| Positive blood culturec | 135 (52.9) | 25 (61) | 1.39 (0.71–2.73) | 0.34 |
| Treatment centre | 0.31 | |||
| – Tertiary care hospital | 28 (11) | 8 (19.5) | reference | |
| – Teaching hospital | 141 (55.3) | 20 (48.8) | 0.50 (0.20–1.24) | |
| – Non-teaching hospital | 86 (33.7) | 13 (31.7) | 0.53 (0.20–1.41) |
aEach patient could have multiple comorbidities.
b Immunodeficiency: drug induced or as the result of an infection with human immunodeficiency virus (HIV).cEach blood culture could contain multiple bacteria.
CI: confidence interval; COPD: chronic obstructive pulmonary disease; ERCP: endoscopic retrograde cholangiopancreatography; IQR: interquartile range; OR: odds ratio.