Table 2.

Diagnostic criteria of COVID-19^a

Classification of the patients	Suspected cases	Clinical confirmed cases (Hubei only)	Pathogenic confirmed cases
Diagnostic basis	Outside Hubei Province: two of the clinical manifestations with at least one of the epidemiological histories, three of the clinical manifestations without epidemiological history	Suspected patient in Hubei Province with CT findings of pneumonia	Suspected or clinically confirmed patients with at least one pathogenic evidence
Epidemiological investigation	1. Travel to or residence in Wuhan in the 14 days prior to symptom onset; 2. Close contactb with SARS-CoV-2 infection (rRT-PCR positive) within 14 days before onset; 3. Exposed to patients from Wuhan and surrounding areas, or from a community with patients who reported fever or respiratory symptoms14 d before onset; 4. Clustering outbreak.	-	-
Clinical manifestations and CT scan	1. Fever and/or respiratory symptoms; 2. Imaging characteristics of COVID-19(CT: multiple small plaque shadows and interstitial changes in early stage, which are obvious in the peripheral lung, and then develop into multiple ground-glass shadows and infiltration shadows in both lungs, and lung consolidation may occur in severe cases); 3. The total number of white blood cells in the early stage is normal or decreased, and the lymphocyte count is decreased	-	-
Pathogenic evidence	NULL	NULL	1. Detection of SARS-CoV-2 in respiratory specimens and sera by rRT-PCR assays; 2. By virus DNA sequencing, respiratory or blood samples DNA sequence highly homologous with SARS-CoV-2.

COVID-19 coronavirus induced disease, SARS-CoV-2 severe acute respiratory syndrome corona virus 2, rRT-PCR real-time reverse transcription-polymerase chain reaction

^aThe diagnostic criteria were defined according to Guidance for the Diagnosis and Management for COVID-19 (5th edition) released by National Health Commission of People’s Republic of China in Feb. 4, 2020 [8]

^bClose contact is defined as follows:

- Healthcare-associated exposure, including providing direct care for COVID-19 patients, working with healthcare workers infected with novel coronavirus, visiting patients, or staying in the same close environment as a COVID-19 patient

- Working together in close proximity or sharing the same classroom environment with a COVID-19 patient

- Traveling together with a COVID-19 patient in any kind of conveyance

- Living in the same household as a COVID-19 patient