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. 2020 Mar 30;9(4):833. doi: 10.3390/cells9040833

Figure 3.

Figure 3

Morpho-functional echocardiographic changes induced by pressure overload in male (n = 19) and female (n = 29) mice subjected to 4-week transverse aortic constriction (TAC). LVMI: left ventricle (LV) mass indexed to body weight (A). PWTI: posterior wall thickness indexed to body weight (B). rPWT: relative posterior wall thickness (2xPWT/LVEDd) (C). LVEF: LV ejection fraction (D). MAPSE: mitral annular plane systolic excursion (E). E/e′: ratio of peak early transmitral flow velocity to peak early myocardial tissue velocity (e′) (F). Data are expressed as means ± SEM. ** p < 0.01; *** p < 0.001 (repeated-measures two-way ANOVA followed by Bonferroni test).