Skip to main content
. 2020 Mar 30;9(4):827. doi: 10.3390/cells9040827

Figure 5.

Figure 5

Oxylipin derived from PUFA. Pro-inflammatory oxylipins are marked in red, while anti-inflammatory ones are marked in blue. The precursor n3-PUFAs are marked in a red square, while the n6-PUFAs are marked in a blue square. COX—cyclooxygenase; LOX—lypooxigenase; CYP—cytochrome P450; NE—nonenzymatic; PGFS—prostaglandin F synthase; PGES—prostaglandin E synthase; PGDS—prostaglandin D synthase; PGIS—prostaglandin I synthase; TXAS—thromboxane A2 synthase; LTAH—leukotriene A4 hydrolase; MDB—membrane dipeptidase; HEDH—hydroxyeicosanoid dehydrogenase; PGDH—hydroxyprostaglandin dehydrogenase; 13-PGR—15-ketoprostaglandin∆13 reductase; sEH—soluble epoxide hydrolase. A list with all the oxylipins can be found in Supplementary Table S1.