Figure 4.

A comparison of examples of primary amino acid sequence from CRF receptors and their closely related GPCRs, seb-2, and diuretic hormone 44 receptors found in the Protein data bank and generated using the multiple alignment tool from NCBI Blast. Red and blue are alignment columns with no gaps, whereas grey residue are aligned with gaps. Highly conserved amino acids are shown in red, and less conserved are shown in blue based on the residues’ relative entropy thresholds.