Table 1.

EC₅₀ values of doxorubicin and SPHK inhibitors in parental and breast CSCs.

Drugs	HCC38		MDA-MB-468
	Parental	CSCs	Parental	CSCs
Doxorubicin (µM)	0.20 ± 0.02	0.59 ± 0.14	0.15 ± 0.04	2.22 ± 1.03
FTY720 (µM)	9.50 ± 0.13	9.04 ± 0.33	5.30 ± 0.14	16.29 ± 0.81
PF543 (µM)	72.86 ± 4.68	33.89 ± 3.67	21.55 ± 7.67	85.98 ± 15.70
ABC294640 (µM)	65.20 ± 6.42	60.85 ± 5.10	22.57 ± 1.02	31.56 ± 3.01
SK1-II (µM)	29.70 ± 11.56	41.36 ± 4.73	7.58 ± 0.52	15.72 ± 5.21