Figure 2.

Cytotoxicity of β-caryophyllene in Mz-ChA-1 cholangiocarcinoma cells (A) and H69 cholangiocytes (B) under both the single long-term exposures of 24 h and 72 h and the metronomic schedule. In the last protocol, the cells were subjected to a single and/or double repeated short exposure of 2 h followed by a recovery time of 72 h. Data are expressed as mean ± SE (standard error) of at least two experiments in which each treatment was tested at least in triplicate (n = 6).