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Cytotoxicity of doxorubicin and its combination with β-caryophyllene in Mz-ChA-1 cholangiocarcinoma cells. (A) Single long-term exposures of 24 h and 72 h. (B) Metronomic schedule: the cells were subjected to a single and/or double repeated short exposure of 2 h followed by a recovery time of 72 h. Data are expressed as mean ± SE (standard error) of at least two experiments in which each treatment was tested at least in triplicate (n = 6).
