Table 3. Calculated Lipophilic Character log P of the Synthesized Compounds.

compd no.	Y	Ar	Ar1	log Pa
3a	−	Ph	−	2.06
3b	−	4-Me-Ph	−	2.50
5a	NH2	Ph	−	3.27
5b	NH2	4-Me-Ph	−	3.72
5c	OH	Ph	−	3.57
5d	OH	4-Me-Ph	−	4.02
9a	NH2	Ph	Ph	4.41
9b	NH2	4-Me-Ph	Ph	4.86
9c	NH2	Ph	4-Me-Ph	4.86
9d	NH2	4-Me-Ph	4-Me-Ph	5.30
9e	NH2	Ph	4-MeO-Ph	4.46
9f	NH2	4-Me-Ph	4-MeO-Ph	4.91
11a	NH2	Ph	−	2.43
11b	NH2	4-Me-Ph	−	2.87
SD				–0.04

^aCalculations were performed using Molinspiration online property calculation toolkit (http://www.molinspiration.com). log P: logarithm of compound partition coefficient between n-octanol and water.