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. 2020 Apr 28;5(18):10401–10414. doi: 10.1021/acsomega.0c00280

Table 7. Inhibition Activity of Compounds 3b, 5a, 5b, 11a, 11b, and TMP at Different Concentrations on the DHFR Enzyme.

compd no. 10 (μg/mL), % 1 (μg/mL), % 0.1 (μg/mL), % 0.01 (μg/mL), %
3b 81.47 60.91 33.38 17.89
5a 75.89 57.27 41.84 29.97
5b 79.44 64.97 37.44 19.80
11a 71.81 66.96 44.13 29.59
11b 60.08 31.25 19.26 12.37
TMP 88.07 66.11 43.02 25.51