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. 2020 May 13;6(5):e03962. doi: 10.1016/j.heliyon.2020.e03962

Table 2.

Anti-nociceptive effects of H. antidysenterica seed extracts in hot plate test.

Latency time (s) (% MPE)
Test Group Dose (mg/kg) Pretreatment 30 min 60 min 90 min
Control Nil 8.00 ± 0.89 8.40 ± 0.40 8.80 ± 0.58 8.40 ± 0.75
Standard 5 10.80 ± 0.37 14.80 ± 0.86∗∗∗(43.48) 16.60 ± 0.51∗∗∗(63.04) 12.40 ± 0.51∗∗ (17.39)
Group I 50 9.80 ± 0.97 11.60 ± 0.51 (17.65) 11.20 ± 0.86 (13.73) 10.80 ± 0.37 (9.80)
Group II 100 10.40 ± 0.51 13.20 ± 1.36∗∗ (29.17) 12.20 ± 0.58∗∗ (18.75) 11.60 ± 1.08 (12.50)
Group III 150 10.80 ± 0.37 17.00 ± 1.27∗∗∗(67.39) 13.60 ± 0.93∗∗∗ (30.43) 13.20 ± 1.02∗∗∗(26.09)

Data values are presented as mean ± SEM (n = 5); MPE, Maximum possible effect; Numbers in parentheses indicates %MPE compared to control; ∗p ˂ 0.05, ∗∗p ˂ 0.01 and ∗∗∗p ˂ 0.001 compared with control group (One way ANOVA with post hoc Dunnett's test).