Table 7.
HSCs migration homing and tracking by bioluminescence.
| Ref. | Substrate | Dose (mg/kg) | Substrate Administration Route | Time Before Image (min) |
Equipment | Software | Animal Position | Exposure Time (min) | Binning | Homing Evaluation Time |
Outcome (Cells Migration) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Astuti et al. [17] | Luciferin | 75# | IP | 10–15 | Xenogen IVIS50 system (Caliper Life Sciences) | Living Image | Dorsal and lateral | 1 | 4; 8 | 98 d | + |
| Saia et al. [20] | Luciferin | 80 | IP | 15 | Xenogen IVIS Lumina system (Caliper, PerkinElmer) | Living Image | Ventral and dorsal | 1 | NR | 1-10 d (20, 30, 40-120 d) | + |
| Lin et al. [18] | Luciferin | 125 | IP | 7 | Xenogen IVIS 200 Imaging system (Caliper Life Sciences) | Living Image | Ventral and dorsal | 5 | NR | 146 d | + |
| Andrade et al. [16] | Luciferin | 125 | IP | 8 | Xenogen IVIS 100 imaging system (Caliber Life Sciences) | Living Image | Ventral and dorsal | 3-1 | NR | 1-65 d | + |
| Ohmori et al. [19] | Luciferin | 1.5§ | IP | NR | IVIS Imaging system (Xenogen, Alameda, CA) | Living Image | Ventral | NR | NR | 3, 7, 14, 21, …, 256 d | + |
| Steiner et al. [11] | Luciferin | 150 | IP | NR | Xenogen-IVIS Imaging system (Caliper Life Sciences Hopkinton, MA) | Living Image | Ventral, dorsal and lateral | 3 -1 s | NR | 7, 14 d (3, 6, 12 months) | + |
| Wang et al. [9] | Luciferin | 125 | IV | 2 | IVIS 3-D optical imaging system (Xenogen, Alameda, CA) | Living Image | Ventral and dorsal | 3-1 | NR | 1, 8 d (7-15 weeks) | + |
Abbreviations—Ref.: reference; IP: intraperitoneal; IV: intravenous; NR: not reported; mg: milligrams; kg: kilograms; μg: microgram; d: days; min: minutes. Note—Units: §: mg/body. #: μg/body.