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. 2020 Apr 10;9(4):934. doi: 10.3390/cells9040934

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effects of DP antagonists on PGD₂-induced neurite outgrowth. Undifferentiated NSC-34 cells were treated with 15 μM PGD₂ in the presence or absence of 10 μM MK0524 or 10 μM CAY10471 for 24 h. (A) Representative phase-contrast microscopy images in each treatment group. Scale bar: 50 μm. (B) Graphs show the percentage of neurite-bearing cells (left panel) and the average neurite length (right panel) in each treatment group. Each value represents the mean ± SEM of four different experiments. ** p < 0.01, *** p < 0.001.