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. 2020 Apr 14;9(4):958. doi: 10.3390/cells9040958

Table 1.

Differences between PC12 and PC12 Adh cell lines [20,21,24,25].

Feature PC12 Cell Line (ATCC CRL-1721) PC12 Adh Cell Line (ATCC CRL-1721.1)
Cell type Cluster of floating cells Adherent cells
Morphology Small and irregular shape Polygonal shape
Culture medium RPMI-1640 with 10% DHS, 5% FBS Ham’s F-12K with 15% DHS, 2.5% FBS
Differentiation/neurite outgrowth Differentiation with NGF or Opti-MEM with 0.5% FBS Neurite outgrowth promoted by Rho kinase (ROCK) inhibition