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. 2020 May 8;11:618. doi: 10.3389/fphar.2020.00618

Figure 3.

Figure 3

BRD4 inhibition restores impaired autophagic influx, but has no effect on autophagy initiation. (A) Immunoblot analysis of LC3B level at 4 h after CCK or CQ stimulation in isolated pancreatic acinar cells (n = 3). (B) Immunoblot analysis of AMPK, mTOR phosphorylation levels at 1 h after CCK stimulation in isolated pancreatic acinar cells (n = 3). (C) mRNA levels of Map1lc3b, Vmp1, Becn1, and Atg2a at 4 h after CCK stimulation (n = 3). Data represent the mean values ± SEM. Statistical analysis was performed by Student’s un-paired, two-tailed t-test between two groups, *P < 0.05, compared to the control; #P < 0.05, compared to CCK-stimulated group;##P < 0.05, compared to the CQ-stimulated group; #P < 0.05, compared to CCK+CQ-stimulated group.