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Protein expression of (A) CD9, (B) CD63, and (C) CD81 in purified small extracellular vesicles (sEVs) from non-physically frail non-sarcopenic (non-PF&S) controls (n = 10) and participants with physical frailty and sarcopenia (PF&S; n = 11). Data were normalized for the amount of sEV total proteins and are shown as percentage of the control group set at 100%. Bars represent mean values (±standard error of the mean). * p < 0.0001 versus non-PF&S.
