Table 2. Fold increase in the expression of genes in PaSCs from WT and Nox1 KO mice with or without CP.

Data are expressed as fold change in gene expression (mean ± SE). 18S rRNA was used as a reference. n: healthy WT: 6; Nox1 KO: 5; WT w/CP: 5; Nox1 KO w/CP: 4.

	WT	KO	WT w/CP	KO w/CP
TGF-B	1.41 ± 0.82	1.57 ± 0.70	9.91 ± 4.99***	0.87 ± 0.55
Slug	1.68 ± 0.80	0.85 ± 0.54	2.40 ± 1.60	1.63 ± 0.32
Zebl	1.49 ± 0.56	0.26 ± 0.15	6.57 ± 1.32*	8.43 ± 1.61*
Zeb2	1.76 ± 0.75	1.53 ± 0.92	1.60 ± 0.51	1.90 ± 0.07
Twist	1.16 ± 0.32	0.31 ± 0.15*	87.81 ± 33.66***	0.93 ± 0.56†††
MMP-9	2.46 ± 1.29	1.47 ± 1.32	4244 ± 2209**	24 ± 17††
Snail	1.18 ± 0.28	1.93 ± 0.98	2.48 ± 0.77	0.84 ± 0.31

^*:p < 0.05,

^**:p < 0.01,

^***:p < 0.001 vs PaSCs from WT mice;

^††:p < 0.01

^†††:p < 0.001 vs PaSCs from WT mice with CP.