Table 2.
Percentage change in absolute lymphocyte count (ALC), CD4+ count, and CD8+ count.
| Mean, ×109/la (n = 476) | Mean % changefrom baselinea | |
|---|---|---|
| ALC | ||
| Baseline | 2.23 | |
| Month 6 | 1.36 (1.31–1.40) | –39 (–41.1– –37.2) |
| Month 12 | 1.24 (1.19–1.29) | –44 (–46.6– –42.1) |
| Month 15 | 1.20 (1.15–1.25) | –46 (–48.3– –43.7) |
| CD4+ | ||
| Baseline | 1.06 | |
| Month 6 | 0.67 (0.64–0.69) | –37 (–39.3– –35.1) |
| Month 12 | 0.61 (0.59–0.64) | –42 (–44.5– –39.8) |
| Month 15 | 0.60 (0.57–0.62) | –44 (–46.2– –41.3) |
| CD8+ | ||
| Baseline | 0.50 | |
| Month 6 | 0.27 (0.25–0.38) | –47 (–49.0– –44.1) |
| Month 12 | 0.24 (0.22–0.25) | –53 (–55.5– –49.9) |
| Month 15 | 0.23 (0.21–0.24) | –55 (–57.6– –51.8) |
Mean values at months 6, 12, and 15 were estimated using a repeated-measures mixed-effects model with baseline ALC, time (log-transformed), and baseline ALC×time interaction effect. Time (log-transformed) was a random effect. Percentage change was estimated from baseline and the estimated mean change.
aValues in parentheses represent mean 95% confidence intervals.